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A narrative review of lumbar medial branch neurotomy for the treatment of back pain

机译:腰内侧支神经切开术治疗背痛的叙事综述

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摘要

Background: Confusion persists concerning the nature and efficacy of procedures variously known as facet denervation, lumbar medial branch radiofrequency neurotomy, and radiofrequency neurotomy or denervation for the treatment of back pain. Systematic reviews have not recognized the importance of patient selection and correct surgical technique when appraising the literature. As a result, negative conclusions about procedures have been drawn because lack of efficacy of one procedure has been misattributed to other, cognate, but different procedures. Objectives: To demonstrate how the rationale and efficacy of lumbar medial branch neurotomy depends critically on correct selection of patients and use of surgically correct technique. Methods: A narrative review and description of the available evidence, drawn from the personal libraries of the authors and from the bibliographies of systematic reviews. Results: Three studies, commonly accepted as evidence of lack of effectiveness, were not valid tests of lumbar medial branch neurotomy because of errors in selection of patients or errors in surgical technique, or both. Two descriptive studies and three controlled studies that used valid or acceptable techniques consistently showed that lumbar medial branch neurotomy had positive effects on pain and disability. All valid, randomized controlled trials showed medial branch neurotomy to be more effective than sham treatment. Discussion: Negative results have been reported only in studies that selected inappropriate patients or used surgically inaccurate techniques. All valid studies showed positive outcomes that cannot be attributed to placebo. Inappropriate conclusions have been drawn by systematic reviews that misrepresent invalid studies as providing evidence against the efficacy of lumbar medial branch neurotomy.
机译:背景:关于手术的性质和功效的困惑依然存在,这些手术被称为小关节去神经,腰内侧支射频神经切开术和射频神经解剖或去神经支配术治疗背痛。在评估文献时,系统评价尚未认识到患者选择和正确手术技术的重要性。结果,由于程序的有效性不足已被归因于其他相同但不同的程序,因此得出了有关程序的负面结论。目的:证明腰椎内侧分支神经切开术的原理和功效如何在很大程度上取决于患者的正确选择和手术正确技术的使用。方法:从作者的个人资料库和系统评价的书目中进行叙述性回顾和对现有证据的描述。结果:三项研究(通常被认为缺乏有效性的证据)由于腰部内侧支神经切开术的选择错误或手术技术错误,或两者都不是有效的测试。使用有效或可接受技术的两项描述性研究和三项对照研究一致表明,腰内侧支神经切开术对疼痛和残疾具有积极作用。所有有效的随机对照试验均显示,内侧支神经切开术比假手术更有效。讨论:仅在选择不适当患者或使用手术不准确技术的研究中报告了阴性结果。所有有效的研究均显示不能归因于安慰剂的积极结果。通过系统评价得出了不适当的结论,这些评价将虚假的研究误认为是对腰内侧分支神经切开术的有效性提供了证据。

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